Expert elicitation on the uncertainties associated with chronic wasting disease.

نویسندگان

  • Michael G Tyshenko
  • Tamer Oraby
  • Shalu Darshan
  • Margit Westphal
  • Maxine C Croteau
  • Willy Aspinall
  • Susie Elsaadany
  • Daniel Krewski
  • Neil Cashman
چکیده

A high degree of uncertainty exists for chronic wasting disease (CWD) transmission factors in farmed and wild cervids. Evaluating the factors is important as it helps to inform future risk management strategies. Expert opinion is often used to assist decision making in a number of health, science, and technology domains where data may be sparse or missing. Using the "Classical Model" of elicitation, a group of experts was asked to estimate the most likely values for several risk factors affecting CWD transmission. The formalized expert elicitation helped structure the issues and hence provide a rational basis for estimating some transmission risk factors for which evidence is lacking. Considered judgments regarding environmental transmission, latency of CWD transmission, management, and species barrier were provided by the experts. Uncertainties for many items were determined to be large, highlighting areas requiring more research. The elicited values may be used as surrogate values until research evidence becomes available.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The use of expert elicitation in environmental health impact assessment: a seven step procedure

BACKGROUND Environmental health impact assessments often have to deal with substantial uncertainties. Typically, the knowledge-base is limited with incomplete, or inconsistent evidence and missing or ambiguous data. Consulting experts can help to identify and address uncertainties. METHODS Formal expert elicitation is a structured approach to systematically consult experts on uncertain issues...

متن کامل

A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease.

The recent research findings concerning syndromes of muscle wasting, malnutrition, and inflammation in individuals with chronic kidney disease (CKD) or acute kidney injury (AKI) have led to a need for new terminology. To address this need, the International Society of Renal Nutrition and Metabolism (ISRNM) convened an expert panel to review and develop standard terminologies and definitions rel...

متن کامل

Human Prion Disease and Relative Risk Associated with Chronic Wasting Disease

The transmission of the prion disease bovine spongiform encephalopathy (BSE) to humans raises concern about chronic wasting disease (CWD), a prion disease of deer and elk. In 7 Colorado counties with high CWD prevalence, 75% of state hunting licenses are issued locally, which suggests that residents consume most regionally harvested game. We used Colorado death certificate data from 1979 throug...

متن کامل

Expert elicitation of the value per statistical life in an air pollution context.

The monetized value of avoided premature mortality typically dominates the calculated benefits of air pollution regulations; therefore, characterization of the uncertainty surrounding these estimates is key to good policymaking. Formal expert judgment elicitation methods are one means of characterizing this uncertainty. They have been applied to characterize uncertainty in the mortality concent...

متن کامل

The concept of probability in safety assessments of technological systems.

Safety assessments of technological systems, such as nuclear power plants, chemical process facilities, and hazardous waste repositories, require the investigation of the occurrence and consequences of rare events. The subjectivistic (Bayesian) theory of probability is the appropriate framework within which expert opinions, which are essential to the quantification process, can be combined with...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of toxicology and environmental health. Part A

دوره 79 16-17  شماره 

صفحات  -

تاریخ انتشار 2016